• Neurona merupakan satu-satunya jurnal yang memuat perkembangan penelitian dan kasus terbaru bidang neurosains di Indonesia. Jurnal ini diterbitkan setiap 3 bulan sekali oleh Perhimpunan Dokter Spesialis Saraf di Indonesia.

  • Sekretariat:
    Departemen Neurologi FKUI/
    RSUPN Dr. Cipto Mangunkusumo

    Jl. Salemba Raya No. 6 Jakarta 10430, Indonesia
    Telp. +62 21 31903219    Fax. +62 21 2305856
    Phone: 081380651980
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Vol. 37 No. 3 Juni 2020


PREVALENSI NYERI NEUROPATIK PADA PASIEN DENGAN NYERI KANKER DI RSUPN DR CIPTO MANGUNKUSUMO DAN PKN RS DHARMAIS
Henry Riyanto Sofyan,* Tiara Aninditha,* Louis Kwandou,**Jonathan Odilo,*** Rini Andriani****
NEUROPATHIC PAIN PREVALENCE AMONG CANCER PAIN PATIENTS IN CIPTO MANGUNKUSUMO AND DHARMAIS HOSPITAL

ABSTRACT

Introduction: Cancer pain is one of the most common complications in cancer. As much as 30-50% of cancer patients experienced pain. Cancer pain patients have reported complaints of pain with a neuropathic component. Early diagnosis of neuropathic cancer pain has a clinical implication for patient management. However, the proportion of neuropathic cancer pain has not been studied in Indonesian population.

Aim: The study was to get an overview of neuropathic pain prevalence among cancer pain patients in Cipto Mangunkusumo General Hospital and National Cancer Referral Dharmais Hospital.

Methods: The design of this research was cross-sectional. The study was done in Cipto Mangunkusumo General Hospital and National Cancer Referral Dharmais Hospital in July-September 2019. The subjects in this research were adult cancer patients who consulted with the Department of Neurology. The data acquired were patient’s demography, cancer history, imaging, and pain assessment. PainDETECT questionnaire was employed to assess neuropathic pain. The data were processed and presented descriptively and analytically.

Results: There were 57 subjects obtained in this research with average age of 45.91. As much as 31.6% subjects had neuropathic cancer pain. Breast cancer identified in 38.6% subjects. There were no differences of gender, age, cancer type, and pain intensity between subjects with and without neuropathic cancer pain. Radiating pain and subject with metastasis experienced neuropathic cancer pain more frequently.

Discussion: The prevalence of neuropathic cancer pain in the Indonesian population is 31.6%. Radiating pain and patients with metastasis cancer tend to experienced neuropathic pain more frequently.

Keywords: Cancer, Indonesia, neuropathic pain, prevalence

ABSTRAK

Pendahuluan: Nyeri kanker merupakan salah satu komplikasi paling sering pada kanker (30-50%). Komponen nyeri neuropatik dapat ditemukan pada pasien. Diagnosis dini nyeri kanker neuropatik memiliki implikasi pada terapi. Namun, proporsi nyeri kanker neuropatik belum pernah diteliti di Indonesia.

Tujuan: Mendapatkan prevalensi dan karakteristik nyeri neuropatik pada pasien nyeri kanker di RSUPN Dr. Cipto Mangunkusumo dan PKN RS Dharmais.

Metode: Penelitian ini dilakukan dengan disain potong lintang terhadap pasien nyeri kanker dewasa yang dikonsultasikan ke bagian Neurologi RSUPN Dr. Cipto Mangunkusumo dan Pusat Kanker Nasional RS Dharmaispada Juli-September 2019. Data yang diambil adalah demografi, riwayat kanker, pencitraan, dan pengkajian nyeri. Deteksi nyeri neuropatik dikaji menggunakan kuesioner PainDETECT yang sudah divalidasi ke dalam Bahasa Indonesia. Data disajikan secara deskriptif dan analitik.

Hasil: Didapatkan 57 subjek dengan rerata usia 45,91. Sebanyak 31,6% pasien mengalami nyeri kanker neuropatik. Kanker payudara didapati pada 38,6% subjek. Tidak terdapat perbedaan bermakna antara jenis kelamin, umur, jenis kanker, dan intensitas nyeri antara subjek dengan dan tanpa nyeri kanker neuropatik. Nyeri menjalar dan subjek dengan metastasis mengalami nyeri neuropatik lebih sering.

Diskusi: Prevalensi nyeri kanker neuropatik pada populasi Indonesia sebesar 31,6%. Nyeri menjalar dan pasien dengan kanker metastasis cenderung mengalami nyeri neuropatik lebih sering.

Kata kunci: Indonesia, nyeri kanker, nyeri neuropatik, prevalensi

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*Departemen Neurologi FK Universitas Indonesia/RSUPN Dr. Cipto Mangunkusumo, Jakarta; **Fellow Neuroonkologi FK Universitas Indonesia, Jakarta/Departemen Neurologi FK Universitas Hasanuddin, Makassar; ***FK Universitas Indonesia, Jakarta; ****SMF Neurologi Pusat Kanker Nasional RS Dharmais, Jakarta.

Korespondensi: henry.riyanto.sofyan@gmail.com.


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