Vol. 34 No. 3 Juni 2017
KADAR PLASMA KARBAMAZEPIN PADA EPILEPSI LOBUS TEMPORAL
Astri Budikayanti,* Herlyani Khosama,** Chiswyta Chaliana,*** Melva Louisa,*** Fitri Octaviana,* Luh Ari Indrawati,* Iswari Setianingsih,**** Teguh Assad Suhatno Ranakusuma,* Rianto Setiabudy***
Introduction: Carbamazepine (CBZ) is drug of choice in the management of temporal lobe epilepsy (TLE), a most common epilepsy syndrome. Nevertheless its plasma level is hard to be predicted due to the auto-induce nature of CBZ. A 400-1600mg dosage range were equal to 4-12mcg/ml plasma level of KBZ. A number of patients are positively respond to low dose of KBZ while other showed sign of intoxication prior to maximum dose.
STRES OKSDATIF OTAK TIKUS PADA INDUKSI HIPOKSIA SISTEMIK KRONIK
Ninik Mudjihartini,* Sri Widia,* Fransiscus Suyatna,** Mohamad Sadikin*
Introduction: Brain is a metabolically active organ which consumes 20% of total oxygen and glucose entering the human body. As a result of high energy metabolism level, brain become more sensitive to oxidative stress.
HUBUNGAN NEUROPATI OTONOM DAN RISIKO OBSTRUCTIVE SLEEP APNEA SYNDROME PADA PASIEN DIABETES MELLITUS TIPE 2
Nushrotul Lailiyya,* Sobaryati,* Miftahurachman,* Marina*
Introduction: High prevalence (58%) of obstructive sleep apnea syndrome (OSAS) has been reported in patients with type 2 diabetes mellitus (T2DM). This mostly found in T2DM patients with obesity and autonomic neuropathy. That is why it is important to know the factors that influence the risk of OSAS for prevention of the disease.
TERAPI INTERVENSI PADA NYERI KEPALA TIPE KLASTER
Hanik Badriyah Hidayati,* Santoso,** Isti Suharjanti,* Mohammad Hasan Machfoed*
ABSTRACT Cluster headache previously known as varian of migrene, is neurovascular headache characterized by unilateral headache and associated with ipsilateral cranial otonomic signs. Diagnosis of cluster headache is made from history taking and physical examination. The main management of cluster headache is pharmacotherapy. In patients with resistant cluster headache regarding pharmacotherapy, interventional therapies such as radiofrequency of pterygopalatine and occipital nerve stimulation are might be needed.
ADAPTASI TRANSKULTURAL KUESIONER PAINDETECT KE DALAM BAHASA INDONESIA
Karolina Margareta,* Tiara Aninditha,* Manfaluthy Hakim,* Herqutanto,** Mohammad Kuniawan*
Introduction: Neuropathic pain is not easily detected due to lack of an ideal screening instrument. Management of neuropathic pain and nociceptic pain are different, nevertheless inadequate management of neuropathic pain will leads to chronic pain that impair quality of life. PainDETECT Questionaire has a high sensitivity and specificity to identify neuropathic pain and already has been translated to various language but not to Indonesian language.
INFECTIOUS ARTERIAL ANEURYSM SEBAGAI MANIFESTASI ENDOKARDITIS BAKTERIALIS
Putu Setiani,* Kumara Tini*
ABSTRACT Infectious arterial aneurysm (IAA) is a rare neurovascular inflammatory lesion IAA develop in an infective endo- carditis (IE) cases when the heart’s fragile vegetation clogging a septic embolic to the intracranial branching vessels. We reported a patient diagnosed as bacterial endocarditis and IAA with main complaint chronic progressive headache.
HUBUNGAN SKOR TROMBOEMBOLI DENGAN SKALA PERFORMA KARNOFSKY PADA PASIEN TUMOR INTRAKRANIAL
Iswandi Erwin,* Yuneldi Anwar,* Irina Kemala Nasution*
Introduction: Patients with malignancy profile especially ones with intracranial tumor are at risk of thrombosis and hemostatic disturbance that could be clinically measured with various thromboembolic scores
HUBUNGAN ASUPAN SERAT PANGAN DENGAN PERUBAHAN KETEBALAN TUNIKA INTIMA MEDIA KAROTIS PASCASTROKE ISKEMIK
Isnawan Widyayanto,* Dodik Tugasworo,* Dwi Pudjonarko*
Introduction: Dietary fiber has protective effect against progression of atherosclerosis through the regulation of serum lipid. Carotid intima-media thickness (cIMT) is a marker of atherosclerosis and related with stroke risk incidence and recurrent stroke.
HUBUNGAN ANTARA JUMLAH NEUTROFIL DAN KADAR HS-CRP SERUM DENGAN LUARAN KLINIS PENDERITA STROKE ISKEMIK
Yohannes William Prasetiyo,* Amin Husni,* Dodik Tugasworo*
Background: Inflammatory response is closely related to the ischemic stroke pathophysiology. Ischemic cascade result in the neuronal death, and activates peripheral immune system. Inflammatory response will damage brain parenchy- mal and determine the clinical outcomes of acute ischemic stroke.
TROMBEKTOMI MEKANIKAL PADA STROKE ISKEMIK DENGAN AWITAN KURANG DARI 6 JAM
Rakhmad Hidayat,* Affan Priyambodho,** Reyhan Eddy Yunus,*** Taufik Mesiano,* Mohammad Kurniawan,* Al Rasyid,* Freddy Sitorus,* Salim Harris,* Teguh Assad Suhatno Ranakusuma*
ABSTRACT We report a case of acute stroke within 3 hour onset admitted to the emergency room Cipto Mangunkusumo Hospital (RSCM), Jakarta. The RSCM Code Stroke protocol was then initiated which included clinical examination and neuroim- aging. Head CT scan showed no intracranial hemorrhage.